Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
Blog Article
1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the treatment of numerous myeloma. Its synthesis or analyze is important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is CAS NO. 875573-66-3 significant for optimizing the production course of action and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to treat breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the remedy of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound hydrochloride is linked to the synthesis of adamantane derivatives, which have numerous programs, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to manage kind 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).